Hepatitis C virus reinfection in injection drug users
نویسندگان
چکیده
منابع مشابه
Hepatitis C virus reinfection in injection drug users.
Spontaneous clearance of hepatitis C (HCV) may provide protection against reinfection. In a large community-based cohort study of 3,553 inner-city residents (mainly injection drug users), we identified HCV-infected individuals in whom virological clearance had occurred and compared the rate of reinfection in this group with that observed in previously uninfected members of the same cohort. We i...
متن کاملMBL2 and Hepatitis C Virus Infection among Injection Drug Users
BACKGROUND Genetic variations in MBL2 that reduce circulating levels and alter functional properties of the mannose binding lectin (MBL) have been associated with many autoimmune and infectious diseases. We examined whether MBL2 variants influence the outcome of hepatitis C virus (HCV) infection. METHODS Participants were enrolled in the Urban Health Study of San Francisco Bay area injection ...
متن کاملFrequent longitudinal sampling of hepatitis C virus infection in injection drug users reveals intermittently detectable viremia and reinfection.
BACKGROUND Detection of hepatitis C virus (HCV) reinfection and intercalation (ie, intermittent recurrent bouts of viremia with homologous virus interspersed with aviremic periods) requires extensive and frequent evaluation and viral sequencing. METHODS HCV infection outcomes were studied prospectively in active injection drug users with recurrent HCV RNA-positive tests after serial negative ...
متن کاملHigh incidence of hepatitis C virus reinfection within a cohort of injecting drug users.
A retrospective cohort study was established of injecting drug users (IDUs) to assess evidence for hepatitis C virus (HCV) protective immunity through a comparison of incidence of initial HCV infection and HCV reinfection. Incidence of initial HCV infection was determined among HCV seronegative IDUs, and HCV reinfection determined among IDUs with newly acquired HCV infection, HCV viraemia and s...
متن کاملPrevention and treatment of hepatitis C in injection drug users.
Injection drug users constitute the largest group of persons infected with the hepatitis C virus (HCV) in the United States, and most new infections occur in drug users. Controlling hepatitis C in the U.S. population, therefore, will require developing, testing, and implementing effective prevention and treatment strategies for persons who inject drugs. Fortunately, a substantial body of resear...
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ژورنال
عنوان ژورنال: Hepatology
سال: 2006
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.21376